Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information.

Autor St Clair, M H, Lambe, C U, Furman, P A
Vydáno 1987

Metabolism of acyclovir in virus-infected and uninfected cells.

Autor Furman, P A, de Miranda, P, St Clair, M H, Elion, G B
Vydáno 1981

Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities.

Autor Furman, P A, Coen, D M, St Clair, M H, Schaffer, P A
Vydáno 1981

Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir.

Autor St Clair, M H, Furman, P A, Lubbers, C M, Elion, G B
Vydáno 1980

Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.

Autor Hall, J D, Furman, P A, St Clair, M H, Knopf, C W
Vydáno 1985

Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89.

Autor Faletto, M B, Miller, W H, Garvey, E P, St Clair, M H, Daluge, S M, Good, S S
Vydáno 1997

Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U.

Autor St Clair, M H, Miller, W H, Miller, R L, Lambe, C U, Furman, P A
Vydáno 1984

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate.

Autor Furman, P A, St Clair, M H, Fyfe, J A, Rideout, J L, Keller, P M, Elion, G B
Vydáno 1979

3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase.

Autor St Clair, M H, Richards, C A, Spector, T, Weinhold, K J, Miller, W H, Langlois, A J, Furman, P A
Vydáno 1987

Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progen...

Autor Dornsife, R E, St Clair, M H, Huang, A T, Panella, T J, Koszalka, G W, Burns, C L, Averett, D R
Vydáno 1991

Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition.

Autor Spector, T, Averett, D R, Nelson, D J, Lambe, C U, Morrison, R W, St Clair, M H, Furman, P A
Vydáno 1985

Human immunodeficiency virus type 1 drug susceptibility during zidovudine (AZT) monotherapy compared with AZT plus 2',3'-dideoxyinosine or AZT plus 2',3'-dideoxycytidine combinatio...

Autor Larder, B A, Kohli, A, Bloor, S, Kemp, S D, Harrigan, P R, Schooley, R T, Lange, J M, Pennington, K N, St Clair, M H
Vydáno 1996

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated viru...

Autor Mitsuya, H, Weinhold, K J, Furman, P A, St Clair, M H, Lehrman, S N, Gallo, R C, Bolognesi, D, Barry, D W, Broder, S
Vydáno 1985

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

Autor Furman, P A, Fyfe, J A, St Clair, M H, Weinhold, K, Rideout, J L, Freeman, G A, Lehrman, S N, Bolognesi, D P, Broder, S, Mitsuya, H
Vydáno 1986

Antiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4(S)-(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol.

Autor Nair, V, St Clair, M H, Reardon, J E, Krasny, H C, Hazen, R J, Paff, M T, Boone, L R, Tisdale, M, Najera, I, Dornsife, R E
Vydáno 1995

5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile.

Autor Daluge, S M, Purifoy, D J, Savina, P M, St Clair, M H, Parry, N R, Dev, I K, Novak, P, Ayers, K M, Reardon, J E, Roberts, G B
Vydáno 1994

1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity.

Autor Daluge, S M, Good, S S, Faletto, M B, Miller, W H, St Clair, M H, Boone, L R, Tisdale, M, Parry, N R, Reardon, J E, Dornsife, R E, Averett, D R, Krenitsky, T A
Vydáno 1997