טוען...
Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.
We present evidence that mutation frequencies in a mammalian system can vary according to the replication fidelity of the DNA polymerase. We demonstrated previously that several derivatives of herpes simplex virus type 1 that encode polymerases resistant to various antiviral drugs (e.g., nucleotide...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
1985
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC397894/ https://ncbi.nlm.nih.gov/pubmed/2987953 |
| תגים: |
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