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High-Frequency Phenotypic Reversion and Pathogenicity of an Acyclovir-Resistant Herpes Simplex Virus Mutant

A double-guanine-insertion mutation within a run of guanines in the herpes simplex virus gene encoding thymidine kinase (TK) was previously found in an acyclovir-resistant clinical isolate. This mutation was engineered into strain KOS, and stocks were generated from single plaques. Plaque autoradiog...

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Bibliografische gegevens
Hoofdauteurs: Griffiths, Anthony, Coen, Donald M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140925/
https://ncbi.nlm.nih.gov/pubmed/12525666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.2282-2286.2003
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