(-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine (524W91) inhibits hepatitis B virus replication in primary human hepatocytes.

Por Condreay, L D, Condreay, J P, Jansen, R W, Paff, M T, Averett, D R
Publicado em 1996

Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in HepG2 derivative 2.2.15 (subclone P5A) cells.

Por Paff, M T, Averett, D R, Prus, K L, Miller, W H, Nelson, D J
Publicado em 1994

In vivo antiviral activity and pharmacokinetics of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in woodchuck hepatitis virus-infected woodchucks.

Por Cullen, J M, Smith, S L, Davis, M G, Dunn, S E, Botteron, C, Cecchi, A, Linsey, D, Linzey, D, Frick, L, Paff, M T, Goulding, A, Biron, K
Publicado em 1997

Antiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4(S)-(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol.

Por Nair, V, St Clair, M H, Reardon, J E, Krasny, H C, Hazen, R J, Paff, M T, Boone, L R, Tisdale, M, Najera, I, Dornsife, R E
Publicado em 1995

Evaluation of the potent anti-hepatitis B virus agent (-) cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in a novel in vivo model.

Por Condreay, L D, Jansen, R W, Powdrill, T F, Johnson, L C, Selleseth, D W, Paff, M T, Daluge, S M, Painter, G R, Furman, P A, Ellis, M N
Publicado em 1994

The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.

Por Furman, P A, Davis, M, Liotta, D C, Paff, M, Frick, L W, Nelson, D J, Dornsife, R E, Wurster, J A, Wilson, L J, Fyfe, J A
Publicado em 1992