The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.

The anti-hepatitis B (anti-HBV) activities of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine (2'-deoxy-3'-thia-5-fluorocytosine [FTC]) were studied by using an HBV-transfected cell line (HepG2 derivative 2.2.15, subclone P5A). The (-) isomer w...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Furman, P A, Davis, M, Liotta, D C, Paff, M, Frick, L W, Nelson, D J, Dornsife, R E, Wurster, J A, Wilson, L J, Fyfe, J A
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2686
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