Загрузка...

Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus.

The pharmacokinetics and metabolism of the potent anti-human immunodeficiency virus and anti-hepatitis B virus compound, (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine (FTC), were investigated in male CD rats. Plasma clearance of 10 mg of FTC per kg of body weight was biexponent...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Frick, L W, St John, L, Taylor, L C, Painter, G R, Furman, P A, Liotta, D C, Furfine, E S, Nelson, D J
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC192380/
https://ncbi.nlm.nih.gov/pubmed/8285607
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!