In vitro susceptibility of varicella-zoster virus to acyclovir.

Por Biron, K K, Elion, G B
Publicado em 1980

"The end of innocence" revisited: resistance of herpesviruses to antiviral drugs.

Por Field, A K, Biron, K K
Publicado em 1994

Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS.

Por Talarico, C L, Phelps, W C, Biron, K K
Publicado em 1993

Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells.

Por Biron, K K, de Miranda, P, Burnette, T C, Krenitsky, T A
Publicado em 1991

Uptake, distribution, and anabolism of acyclovir in herpes simplex virus-infected mice.

Por Biron, K K, Noblin, J E, de Miranda, P, Elion, G B
Publicado em 1982

Anti-human immunodeficiency virus agent 3'-azido-3'-deoxythymidine inhibits replication of Epstein-Barr virus.

Por Lin, J C, Zhang, Z X, Smith, M C, Biron, K, Pagano, J S
Publicado em 1988

Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir.

Por Hanson, M N, Preheim, L C, Chou, S, Talarico, C L, Biron, K K, Erice, A
Publicado em 1995

The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines.

Por He, Z, He, Y S, Kim, Y, Chu, L, Ohmstede, C, Biron, K K, Coen, D M
Publicado em 1997

Anabolic pathway of 6-methoxypurine arabinoside in cells infected with varicella-zoster virus.

Por de Miranda, P, Burnette, T C, Biron, K K, Miller, R L, Averett, D R, Krenitsky, T A
Publicado em 1991

Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir.

Por Stanat, S C, Reardon, J E, Erice, A, Jordan, M C, Drew, W L, Biron, K K
Publicado em 1991

A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.

Por Sullivan, V, Biron, K K, Talarico, C, Stanat, S C, Davis, M, Pozzi, L M, Coen, D M
Publicado em 1993

Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir res...

Por Baldanti, F, Underwood, M R, Stanat, S C, Biron, K K, Chou, S, Sarasini, A, Silini, E, Gerna, G
Publicado em 1996

6-N-substituted derivatives of adenine arabinoside as selective inhibitors of varicella-zoster virus.

Por Koszalka, G W, Averett, D R, Fyfe, J A, Roberts, G B, Spector, T, Biron, K, Krenitsky, T A
Publicado em 1991

Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates.

Por Martin, J L, Ellis, M N, Keller, P M, Biron, K K, Lehrman, S N, Barry, D W, Furman, P A
Publicado em 1985

A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate.

Por Biron, K K, Fyfe, J A, Stanat, S C, Leslie, L K, Sorrell, J B, Lambe, C U, Coen, D M
Publicado em 1986

Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus.

Por Biron, K K, Stanat, S C, Sorrell, J B, Fyfe, J A, Keller, P M, Lambe, C U, Nelson, D J
Publicado em 1985

2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and...

Por Spector, T, Harrington, J A, Morrison, R W, Lambe, C U, Nelson, D J, Averett, D R, Biron, K, Furman, P A
Publicado em 1989

A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.

Por Baldanti, F, Silini, E, Sarasini, A, Talarico, C L, Stanat, S C, Biron, K K, Furione, M, Bono, F, Palù, G, Gerna, G
Publicado em 1995

In vivo antiviral activity and pharmacokinetics of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in woodchuck hepatitis virus-infected woodchucks.

Por Cullen, J M, Smith, S L, Davis, M G, Dunn, S E, Botteron, C, Cecchi, A, Linsey, D, Linzey, D, Frick, L, Paff, M T, Goulding, A, Biron, K
Publicado em 1997