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In vitro susceptibility of varicella-zoster virus to acyclovir.

The in vitro susceptibility of five strains of varicella-zoster virus to acyclovir was examined by the plaque-reduction method in human diploid lung cells. The 50% effective doses of acyclovir ranged from 2.06 microM to 6.28 microM in a 7-day assay, with a mean of 3.65 microM. Irreversible inhibitio...

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Bibliografiske detaljer
Main Authors: Biron, K K, Elion, G B
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC284020/
https://ncbi.nlm.nih.gov/pubmed/6252836
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