Phenotypic and Genetic Characterization of Thymidine Kinase from Clinical Strains of Varicella-Zoster Virus Resistant to Acyclovir

Varicella-zoster virus (VZV) is a common herpesvirus responsible for disseminated or chronic infections in immunocompromised patients. Effective drugs such as acyclovir (ACV), famciclovir (prodrug of penciclovir), and foscarnet are available to treat these infections. Here we report the phenotypic a...

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Main Authors: Morfin, Florence, Thouvenot, Danielle, De Turenne-Tessier, Mireille, Lina, Bruno, Aymard, Michèle, Ooka, Tadamasa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89493/
https://ncbi.nlm.nih.gov/pubmed/10508017
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