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In vitro susceptibility of varicella-zoster virus to acyclovir.

The in vitro susceptibility of five strains of varicella-zoster virus to acyclovir was examined by the plaque-reduction method in human diploid lung cells. The 50% effective doses of acyclovir ranged from 2.06 microM to 6.28 microM in a 7-day assay, with a mean of 3.65 microM. Irreversible inhibitio...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Biron, K K, Elion, G B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6252836/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.3.443
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