A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.

Lignende værker

• Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS.
  af: Baldanti, F, et al.
  Udgivet: (1996)
• The Cys607→Tyr Change in the UL97 Phosphotransferase Confers Ganciclovir Resistance to Two Human Cytomegalovirus Strains Recovered from Two Immunocompromised Patients
  af: Baldanti, Fausto, et al.
  Udgivet: (1998)
• Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.
  af: Lurain, N S, et al.
  Udgivet: (1994)
• Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir.
  af: Hanson, M N, et al.
  Udgivet: (1995)
• Acyclovir Is Phosphorylated by the Human Cytomegalovirus UL97 Protein
  af: Talarico, Christine L., et al.
  Udgivet: (1999)