A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.

Multiple human cytomegalovirus (HCMV) strains frequently coexist in patients with AIDS, and chronic ganciclovir treatment may favor the emergence of ganciclovir-resistant viral mutants. We report the molecular and biochemical characterization of a HCMV ganciclovir-resistant strain (VR3480) previousl...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Baldanti, F, Silini, E, Sarasini, A, Talarico, C L, Stanat, S C, Biron, K K, Furione, M, Bono, F, Palù, G, Gerna, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188644/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.796-800.1995
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