A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.
Multiple human cytomegalovirus (HCMV) strains frequently coexist in patients with AIDS, and chronic ganciclovir treatment may favor the emergence of ganciclovir-resistant viral mutants. We report the molecular and biochemical characterization of a HCMV ganciclovir-resistant strain (VR3480) previousl...
שמור ב:
| הוצא לאור ב: | J Virol |
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| Principais autores: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1995
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188644/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.796-800.1995 |
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