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Metabolism of acyclovir in virus-infected and uninfected cells.

The metabolism of acyclovir to its mono-, di-, and triphosphate derivatives was examined in uninfected and virus-infected cells. The level of phosphorylation of acyclovir was dependent upon virus type, cell line, exogenous drug concentration, and exposure time. Acyclovir phosphorylation was inhibite...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Furman, P A, de Miranda, P, St Clair, M H, Elion, G B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6282196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.20.4.518
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