Metabolism of acyclovir in virus-infected and uninfected cells.

The metabolism of acyclovir to its mono-, di-, and triphosphate derivatives was examined in uninfected and virus-infected cells. The level of phosphorylation of acyclovir was dependent upon virus type, cell line, exogenous drug concentration, and exposure time. Acyclovir phosphorylation was inhibite...

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Hlavní autoři: Furman, P A, de Miranda, P, St Clair, M H, Elion, G B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1981
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC181735/
https://ncbi.nlm.nih.gov/pubmed/6282196
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