C–O bond Formation in a Microfluidic Reactor: High Yield S(N)Ar Substitution of Heteroaryl Chlorides

Por Alam, Mohammad Parvez, Jagodzinska, Barbara, Campagna, Jesus, Spilman, Patricia, John, Varghese
Publicado no Tetrahedron Lett (2016)

Direct Transcriptional Effects of Apolipoprotein E

Por Theendakara, Veena, Peters-Libeu, Clare A., Spilman, Patricia, Poksay, Karen S., Bredesen, Dale E., Rao, Rammohan V.
Publicado no J Neurosci (2016)

Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery

Por Subbiah, Naren, Campagna, Jesus, Spilman, Patricia, Alam, Mohammad Parvez, Sharma, Shivani, Hokugo, Akishige, Nishimura, Ichiro, John, Varghese
Publicado no J Drug Deliv (2017)

The small co-chaperone p23 overexpressing transgenic mouse

Por Zhang, Junli, Spilman, Patricia, Chen, Sylvia, Gorostiza, Olivia, Matalis, Alex, Niazi, Kayvan, Bredesen, Dale E., Rao, Rammohan V.
Publicado em 2012

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

Por Spilman, Patricia, Podlutskaya, Natalia, Hart, Matthew J., Debnath, Jayanta, Gorostiza, Olivia, Bredesen, Dale, Richardson, Arlan, Strong, Randy, Galvan, Veronica
Publicado em 2010

Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

Por Spilman, Patricia, Podlutskaya, Natalia, Hart, Matthew J., Debnath, Jayanta, Gorostiza, Olivia, Bredesen, Dale, Richardson, Arlan, Strong, Randy, Galvan, Veronica
Publicado em 2011

Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

Por Spilman, Patricia, Podlutskaya, Natalia, Hart, Matthew J., Debnath, Jayanta, Gorostiza, Olivia, Bredesen, Dale, Richardson, Arlan, Strong, Randy, Galvan, Veronica
Publicado em 2011

Regular Article: Interaction of ASK1 and the β-Amyloid Precursor Protein in a Stress-Signaling Complex

Por Galvan, Veronica, Banwait, Surita, Spilman, Patricia, Gorostiza, Olivia F., Peel, Alyson, Crippen, Danielle, Sidhu, Gurleen, Ichijo, Hidenori, Bredesen, Dale E.
Publicado em 2007

Paradoxical Effect of TrkA Inhibition in Alzheimer’s Disease Models

Por Zhang, Qiang, Descamps, Olivier, Hart, Matthew J., Poksay, Karen S., Spilman, Patricia, Kane, Darci J., Gorostiza, Olivia, John, Varghese, Bredesen, Dale E.
Publicado em 2014

The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer’s model

Por Spilman, Patricia, Descamps, Olivier, Gorostiza, Olivia, Peters-Libeu, Clare, Poksay, Karen S., Matalis, Alexander, Patent, Alexander, Rao, Rammohan, John, Varghese, Bredesen, Dale E.
Publicado em 2013

AβPP-Selective BACE Inhibitors (ASBI): Novel Class of Therapeutic Agents for Alzheimer’s Disease

Por Descamps, Olivier, Spilman, Patricia, Zhang, Qiang, Libeu, Clare P., Poksay, Karen, Gorostiza, Olivia, Campagna, Jesus, Jagodzinska, Barbara, Bredesen, Dale E., John, Varghese
Publicado em 2013

IN VIVO OXIDATIVE STRESS IN BRAIN OF ALZHEIMER DISEASE TRANSGENIC MICE: REQUIREMENT FOR METHIONINE 35 IN AMYLOID β-PEPTIDE OF APP

Por Butterfield, D. Allan, Galvan, Veronica, Lange, Miranda Bader, Tang, Huidong, Sowell, Renã A., Spilman, Patricia, Fombonne, Joanna, Gorostiza, Olivia, Zhang, Junli, Sultana, Rukhsana, Bredesen, Dale E.
Publicado em 2009

A γ-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains

Por Spilman, Patricia, Lessard, Pierre, Sattavat, Mamta, Bush, Clarissa, Tousseyn, Thomas, Huang, Eric J., Giles, Kurt, Golde, Todd, Das, Pritam, Fauq, Abdul, Prusiner, Stanley B., DeArmond, Stephen J.
Publicado em 2008

Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production

Por Poksay, Karen S., Sheffler, Douglas J., Spilman, Patricia, Campagna, Jesus, Jagodzinska, Barbara, Descamps, Olivier, Gorostiza, Olivia, Matalis, Alex, Mullenix, Michael, Bredesen, Dale E., Cosford, Nicholas D. P., John, Varghese
Publicado no Front Pharmacol (2017)

Endogenously EGFP-Labeled Mouse Embryonic Stem Cells

Por Zhang, Junli, Rao, Rammohan V., Spilman, Patricia, Mangada, Julie, Xie, Lin, Vitelli, Cathy, Gorostiza, Olivia F., Madden, David T., Zeng, Xianmin, Jin, Kunlin, Hart, Matthew J., Bredesen, Dale E., Galvan, Veronica
Publicado em 2011