Nalaganje...

AβPP-Selective BACE Inhibitors (ASBI): Novel Class of Therapeutic Agents for Alzheimer’s Disease

A systematic approach was used to identify AβPP-selective BACE inhibitors (ASBI) and to evaluate their in vivo ability to modulate AβPP processing selectively. We identified a bioflavonoid nutritional supplement as a molecular lead that acts as an ASBI in cell models, and show that increasing brain...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Descamps, Olivier, Spilman, Patricia, Zhang, Qiang, Libeu, Clare P., Poksay, Karen, Gorostiza, Olivia, Campagna, Jesus, Jagodzinska, Barbara, Bredesen, Dale E., John, Varghese
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971881/
https://ncbi.nlm.nih.gov/pubmed/23948888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-130578
Oznake: Označite
Brez oznak, prvi označite!