Next generation therapeutics for Alzheimer's disease

od Bredesen, Dale E, John, Varghese
Izdano 2013

Importance of the Caspase Cleavage Site in Amyloid-β Protein Precursor

od Bredesen, Dale E., John, Varghese, Galvan, Veronica
Izdano 2010

Nanoscale Extracellular Vesicle Analysis in Alzheimer's Disease Diagnosis and Therapy

od Heinzelman, Pete, Bilousova, Tina, Campagna, Jesus, John, Varghese
izdano v Int J Alzheimers Dis (2016)

Ayurvedic medicinal plants for Alzheimer's disease: a review

od Rao, Rammohan V, Descamps, Olivier, John, Varghese, Bredesen, Dale E
Izdano 2012

Structural and Functional Alterations in Amyloid-β Precursor Protein Induced by Amyloid-β Peptides

od Libeu, Clare Peters, Poksay, Karen S., John, Varghese, Bredesen, Dale E.
Izdano 2011

C–O bond Formation in a Microfluidic Reactor: High Yield S(N)Ar Substitution of Heteroaryl Chlorides

od Alam, Mohammad Parvez, Jagodzinska, Barbara, Campagna, Jesus, Spilman, Patricia, John, Varghese
izdano v Tetrahedron Lett (2016)

Altering APP Proteolysis: Increasing sAPPalpha Production by Targeting Dimerization of the APP Ectodomain

od Libeu, Clare A. Peters, Descamps, Olivier, Zhang, Qiang, John, Varghese, Bredesen, Dale E.
Izdano 2012

Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans

od Maccecchini, Maria L, Chang, Mee Young, Pan, Catherine, John, Varghese, Zetterberg, Henrik, Greig, Nigel H
Izdano 2012

Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery

od Subbiah, Naren, Campagna, Jesus, Spilman, Patricia, Alam, Mohammad Parvez, Sharma, Shivani, Hokugo, Akishige, Nishimura, Ichiro, John, Varghese
izdano v J Drug Deliv (2017)

Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor

od Duong, Alexander Tuan-Huy, Simmons, Bryan J., Alam, Mohammad Parvez, Campagna, Jesus, Garg, Neil K., John, Varghese
izdano v Tetrahedron Lett (2018)

High-throughput screening identifies modulators of sarcospan that stabilize muscle cells and exhibit activity in the mouse model of Duchenne muscular dystrophy

od Shu, Cynthia, Parfenova, Liubov, Mokhonova, Ekaterina, Collado, Judd R., Damoiseaux, Robert, Campagna, Jesus, John, Varghese, Crosbie, Rachelle H.
izdano v Skelet Muscle (2020)

Paradoxical Effect of TrkA Inhibition in Alzheimer’s Disease Models

od Zhang, Qiang, Descamps, Olivier, Hart, Matthew J., Poksay, Karen S., Spilman, Patricia, Kane, Darci J., Gorostiza, Olivia, John, Varghese, Bredesen, Dale E.
Izdano 2014

Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2

od Bilousova, Tina, Elias, Chris, Miyoshi, Emily, Alam, Mohammad-Parvez, Zhu, Chunni, Campagna, Jesus, Vadivel, Kanagasabai, Jagodzinska, Barbara, Gylys, Karen, John, Varghese
izdano v Biochem Biophys Res Commun (2018)

The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer’s model

od Spilman, Patricia, Descamps, Olivier, Gorostiza, Olivia, Peters-Libeu, Clare, Poksay, Karen S., Matalis, Alexander, Patent, Alexander, Rao, Rammohan, John, Varghese, Bredesen, Dale E.
Izdano 2013

AβPP-Selective BACE Inhibitors (ASBI): Novel Class of Therapeutic Agents for Alzheimer’s Disease

od Descamps, Olivier, Spilman, Patricia, Zhang, Qiang, Libeu, Clare P., Poksay, Karen, Gorostiza, Olivia, Campagna, Jesus, Jagodzinska, Barbara, Bredesen, Dale E., John, Varghese
Izdano 2013

A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy

od Liu, Jian, Campagna, Jesus, John, Varghese, Damoiseaux, Robert, Mokhonova, Ekaterina, Becerra, Diana, Meng, Huan, McNally, Elizabeth M., Pyle, April D., Kramerova, Irina, Spencer, Melissa J.
izdano v Cell Rep Med (2020)

GoCoronaGo: Privacy Respecting Contact Tracing for COVID-19 Management

od Simmhan, Yogesh, Rambha, Tarun, Khochare, Aakash, Ramesh, Shriram, Baranawal, Animesh, George, John Varghese, Bhope, Rahul Atul, Namtirtha, Amrita, Sundararajan, Amritha, Bhargav, Sharath Suresh, Thakkar, Nihar, Kiran, Raj
izdano v J Indian Inst Sci (2020)

Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production

od Poksay, Karen S., Sheffler, Douglas J., Spilman, Patricia, Campagna, Jesus, Jagodzinska, Barbara, Descamps, Olivier, Gorostiza, Olivia, Matalis, Alex, Mullenix, Michael, Bredesen, Dale E., Cosford, Nicholas D. P., John, Varghese
izdano v Front Pharmacol (2017)

Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model

od Zhu, Chunni, Bilousova, Tina, Focht, Samantha, Jun, Michael, Elias, Chris Jean, Melnik, Mikhail, Chandra, Sujyoti, Campagna, Jesus, Cohn, Whitaker, Hatami, Asa, Spilman, Patricia, Gylys, Karen Hoppens, John, Varghese
izdano v Mol Brain (2021)

Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model

od Zhu, Chunni, Bilousova, Tina, Focht, Samantha, Jun, Michael, Elias, Chris Jean, Melnik, Mikhail, Chandra, Sujyoti, Campagna, Jesus, Cohn, Whitaker, Hatami, Asa, Spilman, Patricia, Gylys, Karen Hoppens, John, Varghese
izdano v Mol Brain (2021)