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Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2
Targeting of molecular pathways involved in the cell-to-cell propagation of pathological tau species is a novel approach for development of disease-modifying therapies that could block tau pathology and attenuate cognitive decline in patients with Alzheimer’s disease and other tauopathies. We discov...
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| Pubblicato in: | Biochem Biophys Res Commun |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5956110/ https://ncbi.nlm.nih.gov/pubmed/29604274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.03.209 |
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