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nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis()
We have previously shown that accumulation of ceramide, triggered by hydrogen peroxide (H(2)O(2)), induces apoptosis of human airway epithelial (HAE) cells. Under oxidant exposure, a lung sphingomyelinase (SMase) is activated and displays continued ceramide generation and pro-apoptotic signaling, th...
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| Publicado en: | Biochem Biophys Res Commun |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4370275/ https://ncbi.nlm.nih.gov/pubmed/16631623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.04.013 |
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