Neutral Sphingomyelinase 2 (nSMase2) Is a Phosphoprotein Regulated by Calcineurin (PP2B)

We previously reported that exposure of human airway epithelial cells to oxidative stress increased ceramide generation via specific activation of neutral sphingomyelinase2 (nSMase2). Here we show that nSMase2 is a phosphoprotein exclusively phosphorylated at serine residues. The level of nSMase2 ph...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Filosto, Simone, Fry, William, Knowlton, Anne A., Goldkorn, Tzipora
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856226/
https://ncbi.nlm.nih.gov/pubmed/20106976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069963
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados