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Src Regulates Cigarette Smoke–Induced Ceramide Generation via Neutral Sphingomyelinase 2 in the Airway Epithelium

We previously demonstrated that the neutral sphingomyelinase (nSMase) 2 is the sole sphingomyelinase activated during cigarette smoke (CS)–induced oxidative stress of human airway epithelial cells, leading to ceramide generation and subsequent apoptosis of affected cells. Since then, we reported tha...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Chung, Samuel, Vu, Simon, Filosto, Simone, Goldkorn, Tzipora
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491128/
https://ncbi.nlm.nih.gov/pubmed/25347576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0122OC
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