Neutral Sphingomyelinase 2: A Novel Target in Cigarette Smoke–Induced Apoptosis and Lung Injury

Chronic obstructive pulmonary disease (COPD) is caused by exposure to cigarette smoke (CS). One mechanism of CS-induced lung injury is aberrant generation of ceramide, which leads to elevated apoptosis of epithelial and endothelial cells in the alveolar spaces. Recently, we discovered that CS-induce...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Filosto, Simone, Castillo, Sianna, Danielson, Aaron, Franzi, Lisa, Khan, Elaine, Kenyon, Nick, Last, Jerold, Pinkerton, Kent, Tuder, Rubin, Goldkorn, Tzipora
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095936/
https://ncbi.nlm.nih.gov/pubmed/20448054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0422OC
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