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Lung Injury and Lung Cancer Caused by Cigarette Smoke-Induced Oxidative Stress: Molecular Mechanisms and Therapeutic Opportunities Involving the Ceramide-Generating Machinery and Epidermal Growth Factor Receptor

Chronic obstructive pulmonary disease (COPD) and lung cancer are frequently caused by tobacco smoking. However, these diseases present opposite phenotypes involving redox signaling at the cellular level. While COPD is characterized by excessive airway epithelial cell death and lung injury, lung canc...

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Detalles Bibliográficos
Main Authors: Goldkorn, Tzipora, Filosto, Simone, Chung, Samuel
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215561/
https://ncbi.nlm.nih.gov/pubmed/24684526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5469
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