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C–O bond Formation in a Microfluidic Reactor: High Yield S(N)Ar Substitution of Heteroaryl Chlorides
This study describes our development of a novel and efficient procedure for C–O bond formation under mild conditions, for coupling heteroaryl chlorides with phenols or primary aliphatic alcohols. We utilized a continuous-flow microfluidic reactor for C–O bond formation in electron-deficient pyrimidi...
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| Pubblicato in: | Tetrahedron Lett |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852388/ https://ncbi.nlm.nih.gov/pubmed/27152054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2016.03.095 |
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