Deletions in BCP-ALL result in a TAD more FLT3

по Spencer, David H.
Опубликовано в: Blood (2020)

Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching

по Spencer, David H., Bubb, Kerry L., Olson, Maynard V.
Опубликовано 2006

Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells

по Ghasemi, Reza, Struthers, Heidi, Wilson, Elisabeth R., Spencer, David H.
Опубликовано в: Leukemia (2020)

Evidence for Diversifying Selection at the Pyoverdine Locus of Pseudomonas aeruginosa

по Smith, Eric E., Sims, Elizabeth H., Spencer, David H., Kaul, Rajinder, Olson, Maynard V.
Опубликовано 2005

DNMT3A(R882)-associated hypomethylation patterns are maintained in primary AML xenografts, but not in the DNMT3A(R882C) OCI-AML3 leukemia cell line

по Chen, David, Christopher, Matthew, Helton, Nichole M., Ferguson, Ian, Ley, Timothy J., Spencer, David H.
Опубликовано в: Blood Cancer J (2018)

Comparison of Clinical Targeted Next-Generation Sequence Data from Formalin-Fixed and Fresh-Frozen Tissue Specimens

по Spencer, David H., Sehn, Jennifer K., Abel, Haley J., Watson, Mark A., Pfeifer, John D., Duncavage, Eric J.
Опубликовано в: J Mol Diagn (2013)

Expression profiling of snoRNAs in normal hematopoiesis and AML

по Warner, Wayne A., Spencer, David H., Trissal, Maria, White, Brian S., Helton, Nichole, Ley, Timothy J., Link, Daniel C.
Опубликовано в: Blood Adv (2018)

Performance of Common Analysis Methods for Detecting Low-Frequency Single Nucleotide Variants in Targeted Next-Generation Sequence Data

по Spencer, David H., Tyagi, Manoj, Vallania, Francesco, Bredemeyer, Andrew J., Pfeifer, John D., Mitra, Rob D., Duncavage, Eric J.
Опубликовано 2014

Inflammatory Cytokines Promote Clonal Hematopoiesis with Specific Mutations in Ulcerative Colitis Patients

по Zhang, Christine RC, Nix, Darren, Gregory, Martin, Ciorba, Matthew A., Ostrander, Elizabeth L., Newberry, Rodney D., Spencer, David H., Challen, Grant A.
Опубликовано в: Exp Hematol (2019)

Whole-Genome Sequence Variation among Multiple Isolates of Pseudomonas aeruginosa

по Spencer, David H., Kas, Arnold, Smith, Eric E., Raymond, Christopher K., Sims, Elizabeth H., Hastings, Michele, Burns, Jane L., Kaul, Rajinder, Olson, Maynard V.
Опубликовано 2003

Genetic Variation at the O-Antigen Biosynthetic Locus in Pseudomonas aeruginosa

по Raymond, Christopher K., Sims, Elizabeth H., Kas, Arnold, Spencer, David H., Kutyavin, Tanya V., Ivey, Richard G., Zhou, Yang, Kaul, Rajinder, Clendenning, James B., Olson, Maynard V.
Опубликовано 2002

The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits WT DNMT3A by Blocking its Ability to Form Active Tetramers

по Russler-Germain, David A., Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Miller, Christopher A., Fulton, Robert, Meyer, Matthew R., Erdmann-Gilmore, Petra, Townsend, R. Reid, Wilson, Richard K., Ley, Timothy J.
Опубликовано 2014

Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

по Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Helton, Nichole M., Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Miller, Christopher A., Klco, Jeffery M., Wilson, Richard K., Ley, Timothy J.
Опубликовано в: Leukemia (2015)

Genomic impact of transient low-dose decitabine treatment on primary AML cells

по Klco, Jeffery M., Spencer, David H., Lamprecht, Tamara L., Sarkaria, Shawn M., Wylie, Todd, Magrini, Vincent, Hundal, Jasreet, Walker, Jason, Varghese, Nobish, Erdmann-Gilmore, Petra, Lichti, Cheryl F., Meyer, Matthew R., Townsend, R. Reid, Wilson, Richard K., Mardis, Elaine R., Ley, Timothy J.
Опубликовано 2013

Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens

по Linette, Gerald P., Becker-Hapak, Michelle, Skidmore, Zachary L., Baroja, Miren Lorea, Xu, Chong, Hundal, Jasreet, Spencer, David H., Fu, Weixuan, Cummins, Casey, Robnett, Maya, Kaabinejadian, Saghar, Hildebrand, William H., Magrini, Vincent, Demeter, Ryan, Krupnick, Alexander S., Griffith, Obi L., Griffith, Malachi, Mardis, Elaine R., Carreno, Beatriz M.
Опубликовано в: Proc Natl Acad Sci U S A (2019)

Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients

по D’Argenio, David A., Wu, Manhong, Hoffman, Lucas R., Kulasekara, Hemantha D., Déziel, Eric, Smith, Eric E., Nguyen, Hai, Ernst, Robert K., Larson Freeman, Theodore J., Spencer, David H., Brittnacher, Mitchell, Hayden, Hillary S., Selgrade, Sara, Klausen, Mikkel, Goodlett, David R., Burns, Jane L., Ramsey, Bonnie W., Miller, Samuel I.
Опубликовано 2007

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

по Klco, Jeffery M., Spencer, David H., Miller, Christopher A., Griffith, Malachi, Lamprecht, Tamara L., O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Fulton, Robert S., Eades, William C., Link, Daniel C., Graubert, Timothy A., Walter, Matthew J., Mardis, Elaine R., Dipersio, John F., Wilson, Richard K., Ley, Timothy J.
Опубликовано 2014

Remethylation of Dnmt3a(−/−) hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

по Ketkar, Shamika, Verdoni, Angela M., Smith, Amanda M., Bangert, Celia V., Leight, Elizabeth R., Chen, David Y., Brune, Meryl K., Helton, Nichole M., Hoock, Mieke, George, Daniel R., Fronick, Catrina, Fulton, Robert S., Ramakrishnan, Sai Mukund, Chang, Gue Su, Petti, Allegra A., Spencer, David H., Miller, Christopher A., Ley, Timothy J.
Опубликовано в: Proc Natl Acad Sci U S A (2020)

CpG island hypermethylation mediated by DNMT3A is a consequence of AML progression

по Spencer, David H., Russler-Germain, David A., Ketkar-Kulkarni, Shamika, Helton, Nichole M., Lamprecht, Tamara L., Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Shinawi, Marwan, Westervelt, Peter, Payton, Jacqueline E., Wartman, Lukas D., Welch, John S., Wilson, Richard K., Walter, Matthew J., Link, Daniel C., DiPersio, John F., Ley, Timothy J.
Опубликовано в: Cell (2017)

Comprehensive discovery of non-coding RNAs in acute myeloid leukemia cell transcriptomes

по Zhang, Jin, Griffith, Malachi, Miller, Christopher A., Griffith, Obi L., Spencer, David H., Walker, Jason R., Magrini, Vincent, McGrath, Sean D., Ly, Amy, Helton, Nichole M., Trissal, Maria, Link, Daniel C., Dang, Ha X., Larson, David E., Kulkarni, Shashikant, Cordes, Matthew G., Fronick, Catrina C., Fulton, Robert S., Klco, Jeffery M., Mardis, Elaine R., Ley, Timothy J., Wilson, Richard K., Maher, Christopher A.
Опубликовано в: Exp Hematol (2017)