Deletions in BCP-ALL result in a TAD more FLT3

par Spencer, David H.
Publié dans Blood (2020)

Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching

par Spencer, David H., Bubb, Kerry L., Olson, Maynard V.
Publié 2006

Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells

par Ghasemi, Reza, Struthers, Heidi, Wilson, Elisabeth R., Spencer, David H.
Publié dans Leukemia (2020)

Evidence for Diversifying Selection at the Pyoverdine Locus of Pseudomonas aeruginosa

par Smith, Eric E., Sims, Elizabeth H., Spencer, David H., Kaul, Rajinder, Olson, Maynard V.
Publié 2005

DNMT3A(R882)-associated hypomethylation patterns are maintained in primary AML xenografts, but not in the DNMT3A(R882C) OCI-AML3 leukemia cell line

par Chen, David, Christopher, Matthew, Helton, Nichole M., Ferguson, Ian, Ley, Timothy J., Spencer, David H.
Publié dans Blood Cancer J (2018)

Comparison of Clinical Targeted Next-Generation Sequence Data from Formalin-Fixed and Fresh-Frozen Tissue Specimens

par Spencer, David H., Sehn, Jennifer K., Abel, Haley J., Watson, Mark A., Pfeifer, John D., Duncavage, Eric J.
Publié dans J Mol Diagn (2013)

Expression profiling of snoRNAs in normal hematopoiesis and AML

par Warner, Wayne A., Spencer, David H., Trissal, Maria, White, Brian S., Helton, Nichole, Ley, Timothy J., Link, Daniel C.
Publié dans Blood Adv (2018)

Performance of Common Analysis Methods for Detecting Low-Frequency Single Nucleotide Variants in Targeted Next-Generation Sequence Data

par Spencer, David H., Tyagi, Manoj, Vallania, Francesco, Bredemeyer, Andrew J., Pfeifer, John D., Mitra, Rob D., Duncavage, Eric J.
Publié 2014

Inflammatory Cytokines Promote Clonal Hematopoiesis with Specific Mutations in Ulcerative Colitis Patients

par Zhang, Christine RC, Nix, Darren, Gregory, Martin, Ciorba, Matthew A., Ostrander, Elizabeth L., Newberry, Rodney D., Spencer, David H., Challen, Grant A.
Publié dans Exp Hematol (2019)

Whole-Genome Sequence Variation among Multiple Isolates of Pseudomonas aeruginosa

par Spencer, David H., Kas, Arnold, Smith, Eric E., Raymond, Christopher K., Sims, Elizabeth H., Hastings, Michele, Burns, Jane L., Kaul, Rajinder, Olson, Maynard V.
Publié 2003

Genetic Variation at the O-Antigen Biosynthetic Locus in Pseudomonas aeruginosa

par Raymond, Christopher K., Sims, Elizabeth H., Kas, Arnold, Spencer, David H., Kutyavin, Tanya V., Ivey, Richard G., Zhou, Yang, Kaul, Rajinder, Clendenning, James B., Olson, Maynard V.
Publié 2002

The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits WT DNMT3A by Blocking its Ability to Form Active Tetramers

par Russler-Germain, David A., Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Miller, Christopher A., Fulton, Robert, Meyer, Matthew R., Erdmann-Gilmore, Petra, Townsend, R. Reid, Wilson, Richard K., Ley, Timothy J.
Publié 2014

Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

par Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Helton, Nichole M., Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Miller, Christopher A., Klco, Jeffery M., Wilson, Richard K., Ley, Timothy J.
Publié dans Leukemia (2015)

Genomic impact of transient low-dose decitabine treatment on primary AML cells

par Klco, Jeffery M., Spencer, David H., Lamprecht, Tamara L., Sarkaria, Shawn M., Wylie, Todd, Magrini, Vincent, Hundal, Jasreet, Walker, Jason, Varghese, Nobish, Erdmann-Gilmore, Petra, Lichti, Cheryl F., Meyer, Matthew R., Townsend, R. Reid, Wilson, Richard K., Mardis, Elaine R., Ley, Timothy J.
Publié 2013

Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens

par Linette, Gerald P., Becker-Hapak, Michelle, Skidmore, Zachary L., Baroja, Miren Lorea, Xu, Chong, Hundal, Jasreet, Spencer, David H., Fu, Weixuan, Cummins, Casey, Robnett, Maya, Kaabinejadian, Saghar, Hildebrand, William H., Magrini, Vincent, Demeter, Ryan, Krupnick, Alexander S., Griffith, Obi L., Griffith, Malachi, Mardis, Elaine R., Carreno, Beatriz M.
Publié dans Proc Natl Acad Sci U S A (2019)

Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients

par D’Argenio, David A., Wu, Manhong, Hoffman, Lucas R., Kulasekara, Hemantha D., Déziel, Eric, Smith, Eric E., Nguyen, Hai, Ernst, Robert K., Larson Freeman, Theodore J., Spencer, David H., Brittnacher, Mitchell, Hayden, Hillary S., Selgrade, Sara, Klausen, Mikkel, Goodlett, David R., Burns, Jane L., Ramsey, Bonnie W., Miller, Samuel I.
Publié 2007

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

par Klco, Jeffery M., Spencer, David H., Miller, Christopher A., Griffith, Malachi, Lamprecht, Tamara L., O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Fulton, Robert S., Eades, William C., Link, Daniel C., Graubert, Timothy A., Walter, Matthew J., Mardis, Elaine R., Dipersio, John F., Wilson, Richard K., Ley, Timothy J.
Publié 2014

Remethylation of Dnmt3a(−/−) hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

par Ketkar, Shamika, Verdoni, Angela M., Smith, Amanda M., Bangert, Celia V., Leight, Elizabeth R., Chen, David Y., Brune, Meryl K., Helton, Nichole M., Hoock, Mieke, George, Daniel R., Fronick, Catrina, Fulton, Robert S., Ramakrishnan, Sai Mukund, Chang, Gue Su, Petti, Allegra A., Spencer, David H., Miller, Christopher A., Ley, Timothy J.
Publié dans Proc Natl Acad Sci U S A (2020)

CpG island hypermethylation mediated by DNMT3A is a consequence of AML progression

par Spencer, David H., Russler-Germain, David A., Ketkar-Kulkarni, Shamika, Helton, Nichole M., Lamprecht, Tamara L., Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Shinawi, Marwan, Westervelt, Peter, Payton, Jacqueline E., Wartman, Lukas D., Welch, John S., Wilson, Richard K., Walter, Matthew J., Link, Daniel C., DiPersio, John F., Ley, Timothy J.
Publié dans Cell (2017)

Comprehensive discovery of non-coding RNAs in acute myeloid leukemia cell transcriptomes

par Zhang, Jin, Griffith, Malachi, Miller, Christopher A., Griffith, Obi L., Spencer, David H., Walker, Jason R., Magrini, Vincent, McGrath, Sean D., Ly, Amy, Helton, Nichole M., Trissal, Maria, Link, Daniel C., Dang, Ha X., Larson, David E., Kulkarni, Shashikant, Cordes, Matthew G., Fronick, Catrina C., Fulton, Robert S., Klco, Jeffery M., Mardis, Elaine R., Ley, Timothy J., Wilson, Richard K., Maher, Christopher A.
Publié dans Exp Hematol (2017)