A Conserved Active Site Tyrosine Residue of Proline Dehydrogenase Helps Enforce the Preference for Proline over Hydroxyproline as the Substrate,

Por Ostrander, Elizabeth L., Larson, John D., Schuermann, Jonathan P., Tanner, John J.
Publicado em 2009

The GNAS(R201C) Mutation Associated with Clonal Hematopoiesis Supports Transplantable Hematopoietic Stem Cell Activity

Por Ostrander, Elizabeth L., Koh, Won Kyun, Mallaney, Cates, Kramer, Ashley C., Wilson, W. Casey, Zhang, Bo, Challen, Grant A.
Publicado no Exp Hematol (2017)

Inflammatory Cytokines Promote Clonal Hematopoiesis with Specific Mutations in Ulcerative Colitis Patients

Por Zhang, Christine RC, Nix, Darren, Gregory, Martin, Ciorba, Matthew A., Ostrander, Elizabeth L., Newberry, Rodney D., Spencer, David H., Challen, Grant A.
Publicado no Exp Hematol (2019)

Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation

Por Celik, Hamza, Mallaney, Cates, Kothari, Alok, Ostrander, Elizabeth L., Eultgen, Elizabeth, Martens, Andrew, Miller, Christopher A., Hundal, Jasreet, Klco, Jeffery M., Challen, Grant A.
Publicado no Blood (2015)

Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness

Por Ostrander, Elizabeth L., Kramer, Ashley C., Mallaney, Cates, Celik, Hamza, Koh, Won Kyun, Fairchild, Jake, Haussler, Emily, Zhang, Christine R.C., Challen, Grant A.
Publicado no Stem Cell Reports (2020)

A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia

Por Xu, Yali, Milazzo, Joseph P., Somerville, Tim D. D., Tarumoto, Yusuke, Huang, Yu-Han, Ostrander, Elizabeth L., Wilkinson, John E., Challen, Grant A., Vakoc, Christopher R.
Publicado no Cancer Cell (2018)

Kdm6b Regulates Context-Dependent Hematopoietic Stem Cell Self-Renewal and Leukemogenesis

Por Mallaney, Cates, Ostrander, Elizabeth L., Celik, Hamza, Kramer, Ashley C., Martens, Andrew, Kothari, Alok, Kyun Koh, Won, Haussler, Emily, Iwamori, Naoki, Gontarz, Paul, Zhang, Bo, Challen, Grant A.
Publicado no Leukemia (2019)

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

Por Jeong, Mira, Park, Hyun Jung, Celik, Hamza, Ostrander, Elizabeth L., Reyes, Jaime M., Guzman, Anna, Rodriguez, Benjamin, Lei, Yong, Lee, Yeojin, Ding, Lei, Guryanova, Olga A., Li, Wei, Goodell, Margaret A., Challen, Grant A.
Publicado no Cell Rep (2018)

Dnmt3a Regulates T-cell Development and Suppresses T-ALL Transformation

Por Kramer, Ashley C., Kothari, Alok, Wilson, W. Casey, Celik, Hamza, Nikitas, John, Mallaney, Cates, Ostrander, Elizabeth L., Eultgen, Elizabeth, Martens, Andrew, Valentine, Mark C., Young, Andrew L., Druley, Todd E., Figueroa, Maria E., Zhang, Bo, Challen, Grant A.
Publicado no Leukemia (2017)

JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

Por Celik, Hamza, Koh, Won Kyun, Kramer, Ashley C., Ostrander, Elizabeth L., Mallaney, Cates, Fisher, Daniel A.C., Xiang, Jingyu, Wilson, William C., Martens, Andrew, Kothari, Alok, Fishberger, Gregory, Tycksen, Eric, Karpova, Darja, Duncavage, Eric J., Lee, Youngsook, Oh, Stephen T., Challen, Grant A.
Publicado no Cancer Cell (2018)