JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

How specific genetic lesions contribute to transformation of non-malignant myeloproliferative neoplasms (MPN) and myelodysplastic syndromes (MDS) to secondary acute myeloid leukemia (sAML) are poorly understood. JARID2 is lost by chromosomal deletions in a proportion of MPN/MDS cases that progress t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Cell
मुख्य लेखकों: Celik, Hamza, Koh, Won Kyun, Kramer, Ashley C., Ostrander, Elizabeth L., Mallaney, Cates, Fisher, Daniel A.C., Xiang, Jingyu, Wilson, William C., Martens, Andrew, Kothari, Alok, Fishberger, Gregory, Tycksen, Eric, Karpova, Darja, Duncavage, Eric J., Lee, Youngsook, Oh, Stephen T., Challen, Grant A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237100/
https://ncbi.nlm.nih.gov/pubmed/30423295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.10.008
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