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A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia
Targeting of general coactivators is an emerging strategy to interfere with oncogenic transcription factors (TFs). However, coactivator perturbations are often pleiotropic and influence numerous TFs. Here we identify TAF12, a subunit of TFIID-SAGA coactivator complexes, as a selective requirement fo...
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| Publicado no: | Cancer Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764110/ https://ncbi.nlm.nih.gov/pubmed/29316427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.12.002 |
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