A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia

Targeting of general coactivators is an emerging strategy to interfere with oncogenic transcription factors (TFs). However, coactivator perturbations are often pleiotropic and influence numerous TFs. Here we identify TAF12, a subunit of TFIID-SAGA coactivator complexes, as a selective requirement fo...

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Detaylı Bibliyografya
Yayımlandı:Cancer Cell
Asıl Yazarlar: Xu, Yali, Milazzo, Joseph P., Somerville, Tim D. D., Tarumoto, Yusuke, Huang, Yu-Han, Ostrander, Elizabeth L., Wilkinson, John E., Challen, Grant A., Vakoc, Christopher R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764110/
https://ncbi.nlm.nih.gov/pubmed/29316427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.12.002
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