Deletions in BCP-ALL result in a TAD more FLT3

por Spencer, David H.
Publicado en Blood (2020)

Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching

por Spencer, David H., Bubb, Kerry L., Olson, Maynard V.
Publicado 2006

Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells

por Ghasemi, Reza, Struthers, Heidi, Wilson, Elisabeth R., Spencer, David H.
Publicado en Leukemia (2020)

Evidence for Diversifying Selection at the Pyoverdine Locus of Pseudomonas aeruginosa

por Smith, Eric E., Sims, Elizabeth H., Spencer, David H., Kaul, Rajinder, Olson, Maynard V.
Publicado 2005

DNMT3A(R882)-associated hypomethylation patterns are maintained in primary AML xenografts, but not in the DNMT3A(R882C) OCI-AML3 leukemia cell line

por Chen, David, Christopher, Matthew, Helton, Nichole M., Ferguson, Ian, Ley, Timothy J., Spencer, David H.
Publicado en Blood Cancer J (2018)

Comparison of Clinical Targeted Next-Generation Sequence Data from Formalin-Fixed and Fresh-Frozen Tissue Specimens

por Spencer, David H., Sehn, Jennifer K., Abel, Haley J., Watson, Mark A., Pfeifer, John D., Duncavage, Eric J.
Publicado en J Mol Diagn (2013)

Expression profiling of snoRNAs in normal hematopoiesis and AML

por Warner, Wayne A., Spencer, David H., Trissal, Maria, White, Brian S., Helton, Nichole, Ley, Timothy J., Link, Daniel C.
Publicado en Blood Adv (2018)

Performance of Common Analysis Methods for Detecting Low-Frequency Single Nucleotide Variants in Targeted Next-Generation Sequence Data

por Spencer, David H., Tyagi, Manoj, Vallania, Francesco, Bredemeyer, Andrew J., Pfeifer, John D., Mitra, Rob D., Duncavage, Eric J.
Publicado 2014

Inflammatory Cytokines Promote Clonal Hematopoiesis with Specific Mutations in Ulcerative Colitis Patients

por Zhang, Christine RC, Nix, Darren, Gregory, Martin, Ciorba, Matthew A., Ostrander, Elizabeth L., Newberry, Rodney D., Spencer, David H., Challen, Grant A.
Publicado en Exp Hematol (2019)

Whole-Genome Sequence Variation among Multiple Isolates of Pseudomonas aeruginosa

por Spencer, David H., Kas, Arnold, Smith, Eric E., Raymond, Christopher K., Sims, Elizabeth H., Hastings, Michele, Burns, Jane L., Kaul, Rajinder, Olson, Maynard V.
Publicado 2003

Genetic Variation at the O-Antigen Biosynthetic Locus in Pseudomonas aeruginosa

por Raymond, Christopher K., Sims, Elizabeth H., Kas, Arnold, Spencer, David H., Kutyavin, Tanya V., Ivey, Richard G., Zhou, Yang, Kaul, Rajinder, Clendenning, James B., Olson, Maynard V.
Publicado 2002

The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits WT DNMT3A by Blocking its Ability to Form Active Tetramers

por Russler-Germain, David A., Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Miller, Christopher A., Fulton, Robert, Meyer, Matthew R., Erdmann-Gilmore, Petra, Townsend, R. Reid, Wilson, Richard K., Ley, Timothy J.
Publicado 2014

Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

por Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Helton, Nichole M., Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Miller, Christopher A., Klco, Jeffery M., Wilson, Richard K., Ley, Timothy J.
Publicado en Leukemia (2015)

Genomic impact of transient low-dose decitabine treatment on primary AML cells

por Klco, Jeffery M., Spencer, David H., Lamprecht, Tamara L., Sarkaria, Shawn M., Wylie, Todd, Magrini, Vincent, Hundal, Jasreet, Walker, Jason, Varghese, Nobish, Erdmann-Gilmore, Petra, Lichti, Cheryl F., Meyer, Matthew R., Townsend, R. Reid, Wilson, Richard K., Mardis, Elaine R., Ley, Timothy J.
Publicado 2013

Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens

por Linette, Gerald P., Becker-Hapak, Michelle, Skidmore, Zachary L., Baroja, Miren Lorea, Xu, Chong, Hundal, Jasreet, Spencer, David H., Fu, Weixuan, Cummins, Casey, Robnett, Maya, Kaabinejadian, Saghar, Hildebrand, William H., Magrini, Vincent, Demeter, Ryan, Krupnick, Alexander S., Griffith, Obi L., Griffith, Malachi, Mardis, Elaine R., Carreno, Beatriz M.
Publicado en Proc Natl Acad Sci U S A (2019)

Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients

por D’Argenio, David A., Wu, Manhong, Hoffman, Lucas R., Kulasekara, Hemantha D., Déziel, Eric, Smith, Eric E., Nguyen, Hai, Ernst, Robert K., Larson Freeman, Theodore J., Spencer, David H., Brittnacher, Mitchell, Hayden, Hillary S., Selgrade, Sara, Klausen, Mikkel, Goodlett, David R., Burns, Jane L., Ramsey, Bonnie W., Miller, Samuel I.
Publicado 2007

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

por Klco, Jeffery M., Spencer, David H., Miller, Christopher A., Griffith, Malachi, Lamprecht, Tamara L., O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Fulton, Robert S., Eades, William C., Link, Daniel C., Graubert, Timothy A., Walter, Matthew J., Mardis, Elaine R., Dipersio, John F., Wilson, Richard K., Ley, Timothy J.
Publicado 2014

Remethylation of Dnmt3a(−/−) hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

por Ketkar, Shamika, Verdoni, Angela M., Smith, Amanda M., Bangert, Celia V., Leight, Elizabeth R., Chen, David Y., Brune, Meryl K., Helton, Nichole M., Hoock, Mieke, George, Daniel R., Fronick, Catrina, Fulton, Robert S., Ramakrishnan, Sai Mukund, Chang, Gue Su, Petti, Allegra A., Spencer, David H., Miller, Christopher A., Ley, Timothy J.
Publicado en Proc Natl Acad Sci U S A (2020)

CpG island hypermethylation mediated by DNMT3A is a consequence of AML progression

por Spencer, David H., Russler-Germain, David A., Ketkar-Kulkarni, Shamika, Helton, Nichole M., Lamprecht, Tamara L., Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Shinawi, Marwan, Westervelt, Peter, Payton, Jacqueline E., Wartman, Lukas D., Welch, John S., Wilson, Richard K., Walter, Matthew J., Link, Daniel C., DiPersio, John F., Ley, Timothy J.
Publicado en Cell (2017)

Comprehensive discovery of non-coding RNAs in acute myeloid leukemia cell transcriptomes

por Zhang, Jin, Griffith, Malachi, Miller, Christopher A., Griffith, Obi L., Spencer, David H., Walker, Jason R., Magrini, Vincent, McGrath, Sean D., Ly, Amy, Helton, Nichole M., Trissal, Maria, Link, Daniel C., Dang, Ha X., Larson, David E., Kulkarni, Shashikant, Cordes, Matthew G., Fronick, Catrina C., Fulton, Robert S., Klco, Jeffery M., Mardis, Elaine R., Ley, Timothy J., Wilson, Richard K., Maher, Christopher A.
Publicado en Exp Hematol (2017)