Substrate Affinity Differentially Influences Protein Kinase C Regulation and Inhibitor Potency

Por Sommese, Ruth F., Sivaramakrishnan, Sivaraj
Publicado no J Biol Chem (2016)

Tuning myosin-driven sorting on cellular actin networks

Por Hariadi, Rizal F, Sommese, Ruth F, Sivaramakrishnan, Sivaraj
Publicado no eLife (2015)

The Role of Regulatory Domains in Maintaining Autoinhibition in the Multidomain Kinase PKCα

Por Sommese, Ruth F., Ritt, Michael, Swanson, Carter J., Sivaramakrishnan, Sivaraj
Publicado no J Biol Chem (2017)

Helicity of short E-R/K peptides

Por Sommese, Ruth F, Sivaramakrishnan, Sivaraj, Baldwin, Robert L, Spudich, James A
Publicado em 2010

Priming GPCR signaling through the synergistic effect of two G proteins

Por Gupte, Tejas M., Malik, Rabia U., Sommese, Ruth F., Ritt, Michael, Sivaramakrishnan, Sivaraj
Publicado no Proc Natl Acad Sci U S A (2017)

Effects of Troponin T Cardiomyopathy Mutations on the Calcium Sensitivity of the Regulated Thin Filament and the Actomyosin Cross-Bridge Kinetics of Human β-Cardiac Myosin

Por Sommese, Ruth F., Nag, Suman, Sutton, Shirley, Miller, Susan M., Spudich, James A., Ruppel, Kathleen M.
Publicado em 2013

Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro

Por Swanson, Carter J., Sommese, Ruth F., Petersen, Karl J., Ritt, Michael, Karslake, Joshua, Thomas, David D., Sivaramakrishnan, Sivaraj
Publicado no PLoS One (2016)

Fluorine substitutions in an antigenic peptide selectively modulate T cell receptor binding in a minimally perturbing manner

Por Piepenbrink, Kurt H., Borbulevych, Oleg Y., Sommese, Ruth F., Clemens, John, Armstrong, Kathryn M., Desmond, Clare, Do, Priscilla, Baker, Brian M.
Publicado em 2009

Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function

Por Sommese, Ruth F., Sung, Jongmin, Nag, Suman, Sutton, Shirley, Deacon, John C., Choe, Elizabeth, Leinwand, Leslie A., Ruppel, Kathleen, Spudich, James A.
Publicado em 2013

T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility

Por Borbulevych, Oleg Y., Piepenbrink, Kurt H., Gloor, Brian E., Scott, Daniel R., Sommese, Ruth F., Cole, David K., Sewell, Andrew K., Baker, Brian M.
Publicado em 2009

Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin

Por Pan, Stephen, Sommese, Ruth F., Sallam, Karim I., Nag, Suman, Sutton, Shirley, Miller, Susan M., Spudich, James A., Ruppel, Kathleen M., Ashley, Euan A.
Publicado no BMC Med Genet (2015)

Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function

Por Nag, Suman, Sommese, Ruth F., Ujfalusi, Zoltan, Combs, Ariana, Langer, Stephen, Sutton, Shirley, Leinwand, Leslie A., Geeves, Michael A., Ruppel, Kathleen M., Spudich, James A.
Publicado no Sci Adv (2015)

Mechanistic Heterogeneity in Contractile Properties of α-Tropomyosin (TPM1) Mutants Associated with Inherited Cardiomyopathies

Por Gupte, Tejas M., Haque, Farah, Gangadharan, Binnu, Sunitha, Margaret S., Mukherjee, Souhrid, Anandhan, Swetha, Rani, Deepa Selvi, Mukundan, Namita, Jambekar, Amruta, Thangaraj, Kumarasamy, Sowdhamini, Ramanathan, Sommese, Ruth F., Nag, Suman, Spudich, James A., Mercer, John A.
Publicado no J Biol Chem (2015)