TMOD-06. MALIGNANT TRANSFORMATION OF PLEXIFORM NEUROFIBROMAS IN AN NF1 MUTANT MOUSE MODEL OF SPINAL IRRADIATION

Tekijä Nakamura, Jean, Laurent, Danny, Smith, Abbi, Bessler, Waylan, Clapp, Wade, Horvai, Andrew
Julkaisussa Neuro Oncol (2020)

EXTH-13. REDUCTION OF TUMOR BURDEN AND HEARING LOSS WITH A MULTIPLE RECEPTOR TYROSINE KINASE INHIBITOR BRIGATINIB IN A GENETICALLY ENGINEERED MOUSE MODEL OF NEUROFIBROMATOSIS TYPE...

Tekijä Smith, Abbi, Bessler, Waylan, Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Masters, Andi, Jones, David, Yates, Charles, Clapp, D Wade
Julkaisussa Neuro Oncol (2018)

Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival

Tekijä Laurent, Danny, Smith, Abbi E, Bessler, Waylan K, Mendonca, Marc, Chin-Sinex, Helen, Descovich, Martina, Horvai, Andrew E, Clapp, D Wade, Nakamura, Jean L
Julkaisussa Neurooncol Adv (2021)

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

Tekijä Wahle, Benjamin M., Hawley, Eric T., He, Yongzheng, Smith, Abbi E., Yuan, Jin, Masters, Andi R., Jones, David R., Gehlhausen, Jeffrey R., Park, Su-Jung, Conway, Simon J., Clapp, D. Wade, Yates, Charles W.
Julkaisussa Oncotarget (2017)

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

Tekijä Rhodes, Steven D, He, Yongzheng, Smith, Abbi, Jiang, Li, Lu, Qingbo, Mund, Julie, Li, Xiaohong, Bessler, Waylan, Qian, Shaomin, Dyer, William, Sandusky, George E, Horvai, Andrew E, Armstrong, Amy E, Clapp, D Wade
Julkaisussa Hum Mol Genet (2019)

Cleveland Clinic International IV Robotics Summit

Tekijä Long, Jordan, Calabrese, Samuel, Al-jedai, Ahmed, Boyd, Anthony, Cotugno, Michael, Dorn, Mitchell, Fanikos, John, Freudiger, Michael J, Kraemer, Irene, Lopez-Cabezas, Carmen, Smith, Abbi, de Stoppelaar, Francine M, Usher, Jerry, Yaniv, Angela W, Knoer, Scott
Julkaisussa Am J Health Syst Pharm (2021)

Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1- Deficient Mice

Tekijä Burks, Ciersten A., Rhodes, Steven D., Bessler, Waylan K., Chen, Shi, Smith, Abbi, Gehlhausen, Jeffrey R., Hawley, Eric T., Jiang, Li, Li, Xiaohong, Yuan, Jin, Lu, Qingbo, Jacobsen, Max, Sandusky, George, Jones, David R., Clapp, D. Wade, Blakeley, Jaishri
Julkaisussa Mol Cancer Ther (2019)

Early Administration of Imatinib Mesylate Reduces Plexiform Neurofibroma Tumor Burden with Durable Results after Drug Discontinuation in a Mouse Model of Neurofibromatosis Type 1

Tekijä Armstrong, Amy E., Rhodes, Steven D., Smith, Abbi, Chen, Shi, Bessler, Waylan, Ferguson, Michael J., Jiang, Li, Li, Xiaohong, Yuan, Jin, Yang, Xianlin, Yang, Feng-Chun, Robertson, Kent A., Ingram, David A., Blakeley, Jaishri O., Clapp, D. Wade
Julkaisussa Pediatr Blood Cancer (2020)

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1

Tekijä Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Julkaisussa J Biol Chem (2020)

Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17

Tekijä Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Julkaisussa J Biol Chem (2020)

Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

Tekijä Gampala, Silpa, Shah, Fenil, Zhang, Chi, Rhodes, Steven D., Babb, Olivia, Grimard, Michelle, Wireman, Randall S., Rad, Ellie, Calver, Brian, Bai, Ren-Yuan, Staedtke, Verena, Hulsey, Emily L., Saadatzadeh, M. Reza, Pollok, Karen E., Tong, Yan, Smith, Abbi E., Clapp, D. Wade, Tee, Andrew R., Kelley, Mark R., Fishel, Melissa L.
Julkaisussa Br J Cancer (2021)

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

Tekijä Gehlhausen, Jeffrey R, Hawley, Eric, Wahle, Benjamin Mark, He, Yongzheng, Edwards, Donna, Rhodes, Steven D, Lajiness, Jacquelyn D, Staser, Karl, Chen, Shi, Yang, Xianlin, Yuan, Jin, Li, Xiaohong, Jiang, Li, Smith, Abbi, Bessler, Waylan, Sandusky, George, Stemmer-Rachamimov, Anat, Stuhlmiller, Timothy J, Angus, Steven P, Johnson, Gary L, Nalepa, Grzegorz, Yates, Charles W, Wade Clapp, D, Park, Su-Jung
Julkaisussa Hum Mol Genet (2019)

Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial

Tekijä Fisher, Michael J., Shih, Chie-Schin, Rhodes, Steven D., Armstrong, Amy E., Wolters, Pamela L., Dombi, Eva, Zhang, Chi, Angus, Steven P., Johnson, Gary L., Packer, Roger J., Allen, Jeffrey C., Ullrich, Nicole J., Goldman, Stewart, Gutmann, David H., Plotkin, Scott R., Rosser, Tena, Robertson, Kent A., Widemann, Brigitte C., Smith, Abbi E., Bessler, Waylan K., He, Yongzheng, Park, Su-Jung, Mund, Julie A., Jiang, Li, Bijangi-Vishehsaraei, Khadijeh, Robinson, Coretta Thomas, Cutter, Gary R., Korf, Bruce R., Blakeley, Jaishri O., Clapp, D. Wade
Julkaisussa Nat Med (2021)

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

Tekijä Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
Julkaisussa PLoS One (2021)