Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival

BACKGROUND: Genetically susceptible individuals can develop malignancies after irradiation of normal tissues. In the context of therapeutic irradiation, it is not known whether irradiating benign neoplasms in susceptible individuals promotes neoplastic transformation and worse clinical outcomes. Ind...

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Bibliografische gegevens
Gepubliceerd in:Neurooncol Adv
Hoofdauteurs: Laurent, Danny, Smith, Abbi E, Bessler, Waylan K, Mendonca, Marc, Chin-Sinex, Helen, Descovich, Martina, Horvai, Andrew E, Clapp, D Wade, Nakamura, Jean L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
Onderwerpen:
Basic and Translational Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193912/
https://ncbi.nlm.nih.gov/pubmed/34131650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab063
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