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Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells
PURPOSE OF REVIEW: Tumorigenic cells can co-opt normal functions of non-malignant hematopoietic cells, promoting tumor progression. Recent mouse and human studies indicate that mast cells underpin inflammation in the plexiform neurofibroma microenvironment of neurofibromatosis type 1. In this model,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539783/ https://ncbi.nlm.nih.gov/pubmed/20571392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0b013e328339511b |
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