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Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells

PURPOSE OF REVIEW: Tumorigenic cells can co-opt normal functions of non-malignant hematopoietic cells, promoting tumor progression. Recent mouse and human studies indicate that mast cells underpin inflammation in the plexiform neurofibroma microenvironment of neurofibromatosis type 1. In this model,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Staser, Karl, Yang, Feng-Chun, Clapp, DW
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539783/
https://ncbi.nlm.nih.gov/pubmed/20571392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0b013e328339511b
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