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Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells

PURPOSE OF REVIEW: Tumorigenic cells can co-opt normal functions of non-malignant hematopoietic cells, promoting tumor progression. Recent mouse and human studies indicate that mast cells underpin inflammation in the plexiform neurofibroma microenvironment of neurofibromatosis type 1. In this model,...

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Bibliografische gegevens
Hoofdauteurs: Staser, Karl, Yang, Feng-Chun, Clapp, DW
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539783/
https://ncbi.nlm.nih.gov/pubmed/20571392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0b013e328339511b
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