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Pathogenesis of Plexiform Neurofibroma: Tumor-Stromal/Hematopoietic Interactions in Tumor Progression

Neurofibromatosis type 1 (NF1) is a genetic disease that results from either heritable or spontaneous autosomal dominant mutations in the NF1 gene. A second-hit mutation precedes the predominant NF1 neoplasms, including myeloid leukemia, optic glioma, and plexiform neurofibroma formation. Despite th...

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Bibliografische gegevens
Hoofdauteurs: Staser, Karl, Yang, Feng-Chun, Clapp, D Wade
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694738/
https://ncbi.nlm.nih.gov/pubmed/22077553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-011811-132441
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