Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas

PURPOSE: Plexiform neurofibromas (pNF) are pathognomonic nerve and soft tissue tumors of neurofibromatosis type I (NF1), which are highly resistant to conventional chemotherapy and associated with significant morbidity/mortality. Disruption of aberrant SCF/c-Kit signaling emanating from the pNF micr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Pediatr Blood Cancer
Hlavní autoři: Ferguson, Michael J., Rhodes, Steven D., Jiang, Li, Li, Xiaohong, Yuan, Jin, Yang, Xianlin, Zhang, Shaobo, Vakili, Saeed T., Territo, Paul, Hutchins, Gary, Yang, Feng-Chun, Ingram, David A., Clapp, D. Wade, Chen, Shi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862309/
https://ncbi.nlm.nih.gov/pubmed/26375012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25763
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky