EXTH-13. REDUCTION OF TUMOR BURDEN AND HEARING LOSS WITH A MULTIPLE RECEPTOR TYROSINE KINASE INHIBITOR BRIGATINIB IN A GENETICALLY ENGINEERED MOUSE MODEL OF NEUROFIBROMATOSIS TYPE 2

Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic disorder caused by germline mutations in the tumor suppressor gene NF2, which encodes the protein Merlin. Patients with NF2 may develop bilateral vestibular schwannomas, which cause hearing impairment, and schwannomas in other regions o...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Smith, Abbi, Bessler, Waylan, Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Masters, Andi, Jones, David, Yates, Charles, Clapp, D Wade
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217088/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.362
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker