EXTH-13. REDUCTION OF TUMOR BURDEN AND HEARING LOSS WITH A MULTIPLE RECEPTOR TYROSINE KINASE INHIBITOR BRIGATINIB IN A GENETICALLY ENGINEERED MOUSE MODEL OF NEUROFIBROMATOSIS TYPE 2

Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic disorder caused by germline mutations in the tumor suppressor gene NF2, which encodes the protein Merlin. Patients with NF2 may develop bilateral vestibular schwannomas, which cause hearing impairment, and schwannomas in other regions o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Smith, Abbi, Bessler, Waylan, Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Masters, Andi, Jones, David, Yates, Charles, Clapp, D Wade
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217088/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.362
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados