TMOD-06. MALIGNANT TRANSFORMATION OF PLEXIFORM NEUROFIBROMAS IN AN NF1 MUTANT MOUSE MODEL OF SPINAL IRRADIATION

von Nakamura, Jean, Laurent, Danny, Smith, Abbi, Bessler, Waylan, Clapp, Wade, Horvai, Andrew
Veröffentlicht in Neuro Oncol (2020)

EXTH-13. REDUCTION OF TUMOR BURDEN AND HEARING LOSS WITH A MULTIPLE RECEPTOR TYROSINE KINASE INHIBITOR BRIGATINIB IN A GENETICALLY ENGINEERED MOUSE MODEL OF NEUROFIBROMATOSIS TYPE...

von Smith, Abbi, Bessler, Waylan, Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Masters, Andi, Jones, David, Yates, Charles, Clapp, D Wade
Veröffentlicht in Neuro Oncol (2018)

Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival

von Laurent, Danny, Smith, Abbi E, Bessler, Waylan K, Mendonca, Marc, Chin-Sinex, Helen, Descovich, Martina, Horvai, Andrew E, Clapp, D Wade, Nakamura, Jean L
Veröffentlicht in Neurooncol Adv (2021)

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

von Wahle, Benjamin M., Hawley, Eric T., He, Yongzheng, Smith, Abbi E., Yuan, Jin, Masters, Andi R., Jones, David R., Gehlhausen, Jeffrey R., Park, Su-Jung, Conway, Simon J., Clapp, D. Wade, Yates, Charles W.
Veröffentlicht in Oncotarget (2017)

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

von Rhodes, Steven D, He, Yongzheng, Smith, Abbi, Jiang, Li, Lu, Qingbo, Mund, Julie, Li, Xiaohong, Bessler, Waylan, Qian, Shaomin, Dyer, William, Sandusky, George E, Horvai, Andrew E, Armstrong, Amy E, Clapp, D Wade
Veröffentlicht in Hum Mol Genet (2019)

Cleveland Clinic International IV Robotics Summit

von Long, Jordan, Calabrese, Samuel, Al-jedai, Ahmed, Boyd, Anthony, Cotugno, Michael, Dorn, Mitchell, Fanikos, John, Freudiger, Michael J, Kraemer, Irene, Lopez-Cabezas, Carmen, Smith, Abbi, de Stoppelaar, Francine M, Usher, Jerry, Yaniv, Angela W, Knoer, Scott
Veröffentlicht in Am J Health Syst Pharm (2021)

Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1- Deficient Mice

von Burks, Ciersten A., Rhodes, Steven D., Bessler, Waylan K., Chen, Shi, Smith, Abbi, Gehlhausen, Jeffrey R., Hawley, Eric T., Jiang, Li, Li, Xiaohong, Yuan, Jin, Lu, Qingbo, Jacobsen, Max, Sandusky, George, Jones, David R., Clapp, D. Wade, Blakeley, Jaishri
Veröffentlicht in Mol Cancer Ther (2019)

Early Administration of Imatinib Mesylate Reduces Plexiform Neurofibroma Tumor Burden with Durable Results after Drug Discontinuation in a Mouse Model of Neurofibromatosis Type 1

von Armstrong, Amy E., Rhodes, Steven D., Smith, Abbi, Chen, Shi, Bessler, Waylan, Ferguson, Michael J., Jiang, Li, Li, Xiaohong, Yuan, Jin, Yang, Xianlin, Yang, Feng-Chun, Robertson, Kent A., Ingram, David A., Blakeley, Jaishri O., Clapp, D. Wade
Veröffentlicht in Pediatr Blood Cancer (2020)

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1

von Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Veröffentlicht in J Biol Chem (2020)

Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17

von Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Veröffentlicht in J Biol Chem (2020)

Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

von Gampala, Silpa, Shah, Fenil, Zhang, Chi, Rhodes, Steven D., Babb, Olivia, Grimard, Michelle, Wireman, Randall S., Rad, Ellie, Calver, Brian, Bai, Ren-Yuan, Staedtke, Verena, Hulsey, Emily L., Saadatzadeh, M. Reza, Pollok, Karen E., Tong, Yan, Smith, Abbi E., Clapp, D. Wade, Tee, Andrew R., Kelley, Mark R., Fishel, Melissa L.
Veröffentlicht in Br J Cancer (2021)

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

von Gehlhausen, Jeffrey R, Hawley, Eric, Wahle, Benjamin Mark, He, Yongzheng, Edwards, Donna, Rhodes, Steven D, Lajiness, Jacquelyn D, Staser, Karl, Chen, Shi, Yang, Xianlin, Yuan, Jin, Li, Xiaohong, Jiang, Li, Smith, Abbi, Bessler, Waylan, Sandusky, George, Stemmer-Rachamimov, Anat, Stuhlmiller, Timothy J, Angus, Steven P, Johnson, Gary L, Nalepa, Grzegorz, Yates, Charles W, Wade Clapp, D, Park, Su-Jung
Veröffentlicht in Hum Mol Genet (2019)

Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial

von Fisher, Michael J., Shih, Chie-Schin, Rhodes, Steven D., Armstrong, Amy E., Wolters, Pamela L., Dombi, Eva, Zhang, Chi, Angus, Steven P., Johnson, Gary L., Packer, Roger J., Allen, Jeffrey C., Ullrich, Nicole J., Goldman, Stewart, Gutmann, David H., Plotkin, Scott R., Rosser, Tena, Robertson, Kent A., Widemann, Brigitte C., Smith, Abbi E., Bessler, Waylan K., He, Yongzheng, Park, Su-Jung, Mund, Julie A., Jiang, Li, Bijangi-Vishehsaraei, Khadijeh, Robinson, Coretta Thomas, Cutter, Gary R., Korf, Bruce R., Blakeley, Jaishri O., Clapp, D. Wade
Veröffentlicht in Nat Med (2021)

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

von Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
Veröffentlicht in PLoS One (2021)