TMOD-06. MALIGNANT TRANSFORMATION OF PLEXIFORM NEUROFIBROMAS IN AN NF1 MUTANT MOUSE MODEL OF SPINAL IRRADIATION

per Nakamura, Jean, Laurent, Danny, Smith, Abbi, Bessler, Waylan, Clapp, Wade, Horvai, Andrew
Publicat a Neuro Oncol (2020)

EXTH-13. REDUCTION OF TUMOR BURDEN AND HEARING LOSS WITH A MULTIPLE RECEPTOR TYROSINE KINASE INHIBITOR BRIGATINIB IN A GENETICALLY ENGINEERED MOUSE MODEL OF NEUROFIBROMATOSIS TYPE...

per Smith, Abbi, Bessler, Waylan, Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Masters, Andi, Jones, David, Yates, Charles, Clapp, D Wade
Publicat a Neuro Oncol (2018)

Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival

per Laurent, Danny, Smith, Abbi E, Bessler, Waylan K, Mendonca, Marc, Chin-Sinex, Helen, Descovich, Martina, Horvai, Andrew E, Clapp, D Wade, Nakamura, Jean L
Publicat a Neurooncol Adv (2021)

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

per Wahle, Benjamin M., Hawley, Eric T., He, Yongzheng, Smith, Abbi E., Yuan, Jin, Masters, Andi R., Jones, David R., Gehlhausen, Jeffrey R., Park, Su-Jung, Conway, Simon J., Clapp, D. Wade, Yates, Charles W.
Publicat a Oncotarget (2017)

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

per Rhodes, Steven D, He, Yongzheng, Smith, Abbi, Jiang, Li, Lu, Qingbo, Mund, Julie, Li, Xiaohong, Bessler, Waylan, Qian, Shaomin, Dyer, William, Sandusky, George E, Horvai, Andrew E, Armstrong, Amy E, Clapp, D Wade
Publicat a Hum Mol Genet (2019)

Cleveland Clinic International IV Robotics Summit

per Long, Jordan, Calabrese, Samuel, Al-jedai, Ahmed, Boyd, Anthony, Cotugno, Michael, Dorn, Mitchell, Fanikos, John, Freudiger, Michael J, Kraemer, Irene, Lopez-Cabezas, Carmen, Smith, Abbi, de Stoppelaar, Francine M, Usher, Jerry, Yaniv, Angela W, Knoer, Scott
Publicat a Am J Health Syst Pharm (2021)

Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1- Deficient Mice

per Burks, Ciersten A., Rhodes, Steven D., Bessler, Waylan K., Chen, Shi, Smith, Abbi, Gehlhausen, Jeffrey R., Hawley, Eric T., Jiang, Li, Li, Xiaohong, Yuan, Jin, Lu, Qingbo, Jacobsen, Max, Sandusky, George, Jones, David R., Clapp, D. Wade, Blakeley, Jaishri
Publicat a Mol Cancer Ther (2019)

Early Administration of Imatinib Mesylate Reduces Plexiform Neurofibroma Tumor Burden with Durable Results after Drug Discontinuation in a Mouse Model of Neurofibromatosis Type 1

per Armstrong, Amy E., Rhodes, Steven D., Smith, Abbi, Chen, Shi, Bessler, Waylan, Ferguson, Michael J., Jiang, Li, Li, Xiaohong, Yuan, Jin, Yang, Xianlin, Yang, Feng-Chun, Robertson, Kent A., Ingram, David A., Blakeley, Jaishri O., Clapp, D. Wade
Publicat a Pediatr Blood Cancer (2020)

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1

per Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Publicat a J Biol Chem (2020)

Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17

per Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Publicat a J Biol Chem (2020)

Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

per Gampala, Silpa, Shah, Fenil, Zhang, Chi, Rhodes, Steven D., Babb, Olivia, Grimard, Michelle, Wireman, Randall S., Rad, Ellie, Calver, Brian, Bai, Ren-Yuan, Staedtke, Verena, Hulsey, Emily L., Saadatzadeh, M. Reza, Pollok, Karen E., Tong, Yan, Smith, Abbi E., Clapp, D. Wade, Tee, Andrew R., Kelley, Mark R., Fishel, Melissa L.
Publicat a Br J Cancer (2021)

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

per Gehlhausen, Jeffrey R, Hawley, Eric, Wahle, Benjamin Mark, He, Yongzheng, Edwards, Donna, Rhodes, Steven D, Lajiness, Jacquelyn D, Staser, Karl, Chen, Shi, Yang, Xianlin, Yuan, Jin, Li, Xiaohong, Jiang, Li, Smith, Abbi, Bessler, Waylan, Sandusky, George, Stemmer-Rachamimov, Anat, Stuhlmiller, Timothy J, Angus, Steven P, Johnson, Gary L, Nalepa, Grzegorz, Yates, Charles W, Wade Clapp, D, Park, Su-Jung
Publicat a Hum Mol Genet (2019)

Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial

per Fisher, Michael J., Shih, Chie-Schin, Rhodes, Steven D., Armstrong, Amy E., Wolters, Pamela L., Dombi, Eva, Zhang, Chi, Angus, Steven P., Johnson, Gary L., Packer, Roger J., Allen, Jeffrey C., Ullrich, Nicole J., Goldman, Stewart, Gutmann, David H., Plotkin, Scott R., Rosser, Tena, Robertson, Kent A., Widemann, Brigitte C., Smith, Abbi E., Bessler, Waylan K., He, Yongzheng, Park, Su-Jung, Mund, Julie A., Jiang, Li, Bijangi-Vishehsaraei, Khadijeh, Robinson, Coretta Thomas, Cutter, Gary R., Korf, Bruce R., Blakeley, Jaishri O., Clapp, D. Wade
Publicat a Nat Med (2021)

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

per Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
Publicat a PLoS One (2021)