Crystallization and preliminary X-ray analysis of 6-­hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus

por Chhabra, Sandeep, Newman, Janet, Peat, Thomas S., Fernley, Ross T., Caine, Joanne, Simpson, Jamie S., Swarbrick, James D.
Publicado 2010

Intensive Referral to Mutual-Help Groups: A Field Trial of Adaptations for Rural Veterans

por Grant, Kathleen M., Young, Lance Brendan, Tyler, Kimberly A., Simpson, Jamie L., Pulido, R. Dario, Timko, Christine
Publicado en Patient Educ Couns (2017)

Intensive Referral of Veterans to Mutual-Help Groups: A Mixed-Methods Implementation Evaluation

por Young, Lance Brendan, Grant, Kathleen M., Pulido, R. Dario, Simpson, Jamie L., Tyler, Kimberly A., Timko, Christine
Publicado en Alcohol Treat Q (2017)

Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor

por Chhabra, Sandeep, Dolezal, Olan, Collins, Brett M., Newman, Janet, Simpson, Jamie S., Macreadie, Ian G., Fernley, Ross, Peat, Thomas S., Swarbrick, James D.
Publicado 2012

Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK

por Vinh, Natalie B, Devine, Shane M, Munoz, Lenka, Ryan, Renae M, Wang, Bing H, Krum, Henry, Chalmers, David K, Simpson, Jamie S, Scammells, Peter J
Publicado en ChemistryOpen (2015)

Molecular Insights into the Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and an Invasion-Inhibitory Peptide

por Wang, Geqing, MacRaild, Christopher A., Mohanty, Biswaranjan, Mobli, Mehdi, Cowieson, Nathan P., Anders, Robin F., Simpson, Jamie S., McGowan, Sheena, Norton, Raymond S., Scanlon, Martin J.
Publicado 2014

The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide

por Chin, Yanni K.-Y., Headey, Stephen J., Mohanty, Biswaranjan, Patil, Rahul, McEwan, Paul A., Swarbrick, James D., Mulhern, Terrence D., Emsley, Jonas, Simpson, Jamie S., Scanlon, Martin J.
Publicado 2013

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening

por La, Jennifer, Latham, Catherine F., Tinetti, Ricky N., Johnson, Adam, Tyssen, David, Huber, Kelly D., Sluis-Cremer, Nicolas, Simpson, Jamie S., Headey, Stephen J., Chalmers, David K., Tachedjian, Gilda
Publicado en Proc Natl Acad Sci U S A (2015)

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

por Mohanty, Biswaranjan, Rimmer, Kieran, McMahon, Róisín M., Headey, Stephen J., Vazirani, Mansha, Shouldice, Stephen R., Coinçon, Mathieu, Tay, Stephanie, Morton, Craig J., Simpson, Jamie S., Martin, Jennifer L., Scanlon, Martin J.
Publicado en PLoS One (2017)

The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes

por Paxman, Jason J., Borg, Natalie A., Horne, James, Thompson, Philip E., Chin, Yanni, Sharma, Pooja, Simpson, Jamie S., Wielens, Jerome, Piek, Susannah, Kahler, Charlene M., Sakellaris, Harry, Pearce, Mary, Bottomley, Stephen P., Rossjohn, Jamie, Scanlon, Martin J.
Publicado 2009

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

por Jensen, Dane D., Lieu, TinaMarie, Halls, Michelle L., Veldhuis, Nicholas A., Imlach, Wendy L., Mai, Quynh N., Poole, Daniel P., Quach, Tim, Aurelio, Luigi, Conner, Joshua, Herenbrink, Carmen Klein, Barlow, Nicholas, Simpson, Jamie S., Scanlon, Martin J., Graham, Bimbil, McCluskey, Adam, Robinson, Phillip J., Escriou, Virginie, Nassini, Romina, Materazzi, Serena, Geppetti, Pierangelo, Hicks, Gareth A., Christie, Macdonald J., Porter, Christopher J. H., Canals, Meritxell, Bunnett, Nigel W.
Publicado en Sci Transl Med (2017)