Deep sequencing as a probe of normal stem cell fate and preneoplasia in human epidermis

Por Simons, Benjamin D.
Publicado no Proc Natl Acad Sci U S A (2016)

Reply to Martincorena et al.: Evidence for constrained positive selection of cancer mutations in normal skin is lacking

Por Simons, Benjamin D.
Publicado no Proc Natl Acad Sci U S A (2016)

Dynamic heterogeneity as a strategy of stem cell self-renewal

Por Greulich, Philip, Simons, Benjamin D.
Publicado no Proc Natl Acad Sci U S A (2016)

Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo

Por Amoyel, Marc, Simons, Benjamin D, Bach, Erika A
Publicado no EMBO J (2014)

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia

Por Klein, Allon M., Brash, Douglas E., Jones, Philip H., Simons, Benjamin D.
Publicado em 2009

The Independent Probabilistic Firing of Transcription Factors: A Paradigm for Clonal Variability in the Zebrafish Retina

Por Boije, Henrik, Rulands, Steffen, Dudczig, Stefanie, Simons, Benjamin D., Harris, William A.
Publicado no Dev Cell (2015)

Uncovering the Number and Clonal Dynamics of Mesp1 Progenitors during Heart Morphogenesis

Por Chabab, Samira, Lescroart, Fabienne, Rulands, Steffen, Mathiah, Navrita, Simons, Benjamin D., Blanpain, Cédric
Publicado no Cell Rep (2015)

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

Por Otani, Tomoki, Marchetto, Maria C., Gage, Fred H., Simons, Benjamin D., Livesey, Frederick J.
Publicado no Cell Stem Cell (2016)

Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells

Por Wuidart, Aline, Ousset, Marielle, Rulands, Steffen, Simons, Benjamin D., Van Keymeulen, Alexandra, Blanpain, Cédric
Publicado no Genes Dev (2016)

Patterning as a signature of human epidermal stem cell regulation

Por Klein, Allon M., Nikolaidou-Neokosmidou, Varvara, Doupé, David P., Jones, Philip H., Simons, Benjamin D.
Publicado em 2011

How Variable Clones Build an Invariant Retina

Por He, Jie, Zhang, Gen, Almeida, Alexandra D., Cayouette, Michel, Simons, Benjamin D., Harris, William A.
Publicado em 2012

Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion

Por Snippert, Hugo J, Schepers, Arnout G, van Es, Johan H, Simons, Benjamin D, Clevers, Hans
Publicado em 2014

Mouse Spermatogenic Stem Cells Continually Interconvert between Equipotent Singly Isolated and Syncytial States

Por Hara, Kenshiro, Nakagawa, Toshinori, Enomoto, Hideki, Suzuki, Mikiko, Yamamoto, Masayuki, Simons, Benjamin D., Yoshida, Shosei
Publicado em 2014

Differentiation imbalance in single Oesophageal progenitor cells causes clonal immortalization and field change

Por Alcolea, Maria P., Greulich, Philip, Wabik, Agnieszka, Frede, Julia, Simons, Benjamin D., Jones, Philip H.
Publicado em 2014

Stem and progenitor cell division kinetics during postnatal mouse mammary gland development

Por Giraddi, Rajshekhar R., Shehata, Mona, Gallardo, Mercedes, Blasco, Maria A., Simons, Benjamin D., Stingl, John
Publicado no Nat Commun (2015)

Human Keratinocytes have two interconvertible modes of proliferation

Por Roshan, Amit, Murai, Kasumi, Fowler, Joanna, Simons, Benjamin D, Nikolaidou-Neokosmidou, Varvara, Jones, Philip H
Publicado no Nat Cell Biol (2015)

Defining stem cell dynamics and migration during wound healing in mouse skin epidermis

Por Aragona, Mariaceleste, Dekoninck, Sophie, Rulands, Steffen, Lenglez, Sandrine, Mascré, Guilhem, Simons, Benjamin D., Blanpain, Cédric
Publicado no Nat Commun (2017)

Cell Competition Modifies Adult Stem Cell and Tissue Population Dynamics in a JAK-STAT-Dependent Manner

Por Kolahgar, Golnar, Suijkerbuijk, Saskia J.E., Kucinski, Iwo, Poirier, Enzo Z., Mansour, Sarah, Simons, Benjamin D., Piddini, Eugenia
Publicado no Dev Cell (2015)

Defining the clonal dynamics leading to mouse skin tumour initiation

Por Sánchez-Danés, Adriana, Hannezo, Edouard, Larsimont, Jean-Christophe, Liagre, Mélanie, Youssef, Khalil Kass, Simons, Benjamin D, Blanpain, Cédric
Publicado no Nature (2016)

A single progenitor population switches behavior to maintain and repair esophageal epithelium

Por Doupé, David P., Alcolea, Maria P., Roshan, Amit, Zhang, Gen, Klein, Allon M., Simons, Benjamin D., Jones, Philip H.
Publicado em 2012