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Differentiation imbalance in single Oesophageal progenitor cells causes clonal immortalization and field change
Multiple cancers may arise from within a clonal region of preneoplastic epithelium, a phenomenon termed ‘field change’(1, 2). However, it is not known how field change develops. Here we investigate this question using lineage tracing to track the behaviour of scattered single oesophageal epithelial...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085550/ https://ncbi.nlm.nih.gov/pubmed/24814514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2963 |
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