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A single progenitor population switches behavior to maintain and repair esophageal epithelium

Diseases of esophageal epithelium (EE) such as reflux esophagitis and cancer are rising in incidence. Despite this, the cellular behaviors underlying EE homeostasis and repair remain controversial. Here we show that in mice, EE is maintained by a single population of cells that divide stochastically...

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Detalhes bibliográficos
Main Authors: Doupé, David P., Alcolea, Maria P., Roshan, Amit, Zhang, Gen, Klein, Allon M., Simons, Benjamin D., Jones, Philip H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527005/
https://ncbi.nlm.nih.gov/pubmed/22821983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218835
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