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Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium
The DNA methyltransferase Dnmt1 maintains DNA methylation patterns and genomic stability in several in vitro cell systems. Ablation of Dnmt1 in mouse embryos causes death at the post-gastrulation stage; however, the functions of Dnmt1 and DNA methylation in organogenesis remain unclear. Here, we rep...
Gespeichert in:
| Veröffentlicht in: | Development |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4483766/ https://ncbi.nlm.nih.gov/pubmed/26023099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117341 |
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