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DNA methylation is required for the control of stem cell differentiation in the small intestine
The mammalian intestinal epithelium has a unique organization in which crypts harboring stem cells produce progenitors and finally clonal populations of differentiated cells. Remarkably, the epithelium is replaced every 3–5 d throughout adult life. Disrupted maintenance of the intricate balance of p...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967052/ https://ncbi.nlm.nih.gov/pubmed/24637118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.230318.113 |
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