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Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation
Methylated cytosines are associated with gene silencing. The ten-eleven translocation (TET) hydroxylases, which oxidize methylated cytosines to 5-hydroxymethylcytosine (5hmC), are essential for cytosine demethylation. Gene silencing and activation are critical for intestinal stem cell (ISC) maintena...
Gorde:
| Argitaratua izan da: | Genes Dev |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Cold Spring Harbor Laboratory Press
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131782/ https://ncbi.nlm.nih.gov/pubmed/27856615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.288035.116 |
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