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5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulation
BACKGROUND: Recent mapping of 5-hydroxymethylcytosine (5hmC) provides a genome-wide view of the distribution of this important chromatin mark. However, the role of 5hmC in specific regulatory regions is not clear, especially at enhancers. RESULTS: We found a group of distal transcription factor bind...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133056/ https://ncbi.nlm.nih.gov/pubmed/25106691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-670 |
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